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Selected publications

The Quality Management of the Medical University Innsbruck (MUI) evaluated all publications and established a list including links to PubMed for papers published after 01/01/1997. The papers listed here reflect key results of our own work and important contributions to projects by other groups.

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2012

Hensel N, Ratzka A, Brinkmann H, Klimaschewski L, Grothe C, Claus P. Analysis of the Fibroblast Growth Factor system reveals alterations in a mouse model of Spinal Muscular Atrophy. PLOS ONE

Soumen R, Johnston AH, Moin ST, Dudas J, Newman TA, Hausott B, Schrott-Fischera A, Glueckert R. Activation of TrkB receptors by NGFβ mimetic peptide conjugated polymersome nanoparticles. NANOMEDICINE

Hausott B, Vallant N, Hochfilzer M, Mangger S, Irschick R, Haugsten EM, Klimaschewski L. Leupeptin enhances cell surface localization of fibroblast growth factor receptor 1 in sensory neurons by increased recycling. EUROPEAN JOURNAL OF CELL BIOLOGY

Hausott B, Vallant N, Schlick B, Schwarzer C, Dai F, Brand-Saberi B, Klimaschewski L.  Sprouty2 and -4 regulate axon outgrowth by hippocampal neurons. HIPPOCAMPUS


2011

Hausott B, Rietzler A, Vallant N, Auer M, Haller I, Perkhofer S, Klimaschewski L. Inhibition of fibroblast growth factor receptor 1 endocytosis promotes axonal branching of adult sensory neurons. NEUROSCIENCE, 188, 13

Auer M, Hausott B, Klimaschewski L. Rho GTPases as regulators of morphological neuroplasticity. ANNALS OF ANATOMY (Special Issue), 193, 259


2010

Boato F, Hendrix S, Huelsenbeck SC, Hofmann F, Grosse G, Djalali S, Klimaschewski L, Auer M, Just I, Ahnert-Hilger G, Höltje M. C3 peptide enhances recovery from spinal cord injury by improved regenerative growth of descending fiber tracts. JOURNAL OF CELL SCIENCE, 123, 1652

Lang L, Ingorokva S, Hausott B, Vallant N, Schmidt S, Schwarzer C, Klimaschewski L. Selective up-regulation of the vasodilator peptide apelin after nerve root but not after spinal nerve injury. NEUROSCIENCE, 170, 954


2009

Hausott B, Vallant N, Auer M, Yang L, Dai F, Brand-Saberi B, Klimaschewski L. Sprouty2 down-regulation promotes peripheral axon regeneration by adult sensory neurons. MOLECULAR AND CELLULAR NEUROSCIENCE, 42, 328


2008

Hausott B, Schlick B, Vallant N, Dorn R, Klimaschewski L. Promotion of neurite outgrowth by FGFR1 overexpression and lysosomal inhibition of receptor degradation in PC12 cells and adult sensory neurons. NEUROSCIENCE, 153, 461


2007

Dieplinger B, Schiefermeier N, Juchum-Pasquazzo M, Gstir R, Huber LA, Klimaschewski L (corr. A.), Vietor I (corr. A.). The transcriptional co-repressor TIS7 regulates adult axon growth through CRABP II expression. EUROPEAN JOURNAL OF NEUROSCIENCE, 26, 3358

Schweigreiter R,  Stasyk T, Contarini I, Frauscher S,  Oertle T, Klimaschewski L,  Huber L, Bandtlow C. Phosphorylation-regulated Cleavage of the Reticulon Protein Nogo-B by Caspase-7 at a Noncanonical Recognition Site. PROTEOMICS, 7, 4457


2006

Klimaschewski L, Hausott B, Ingorokva S, Pfaller K. Constitutively expressed catalytic proteasomal subunits are up-regulated during neuronal differentiation and required for axon initiation, elongation and maintenance. JOURNAL OF NEUROCHEMISTRY, 96, 1708

Suarez V, Ingorokva S, Guntinas-Lichius O, Streppel M, Grosheva M, Neiss W, Angelov D, Klimaschewski L. The axotomy-induced neuropeptides galanin and PACAP promote axonal sprouting of primary afferent and cranial motor neurons. EUROPEAN JOURNAL OF NEUROSCIENCE, 24, 1555

Lirk P, Haller I, Myers RR, Klimaschewski L, Kau YC, Hung YC,  Gerner P. Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo. ANESTHESIOLOGY, 104, 1266

Haller I, Hausott B, Tomaselli B, Keller C, Gerner P, Klimaschewski L, Lirk P. Neurotoxicity of lidocaine involves specific activation of the p38 mitogen-activated protein kinase, but not ERK/JNK, and is mediated by arachidonic acid metabolites. ANESTHESIOLOGY, 105, 1024


2005

Tomasino A, Klimaschewski L. Tissue distribution of the ‘N-end rule’ ubiquitin carrier protein, E214kD (UBC2). HISTOCHEMISTRY AND CELL BIOLOGY, 123, 483

Kavakebi P, Hausott B, Tomasino A, Ingorokva S, Klimaschewski L. The N-end rule ubiquitin conjugating enzyme, HR6B, is up-regulated by nerve growth factor and required for neurite outgrowth. MOLECULAR AND CELLULAR NEUROSCIENCE, 29, 559


2000-2004

Angelastro JM, Klimaschewski L, Tang S, Vittolo OV, Weissman TA, Donlin LT, Shelanski ML, Greene LA. Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA), 2000, 97, 10424

Stefanova N, Klimaschewski L, Poewe W, Wenning GK, Reindl M. Glial cell death induced by overexpression of alpha-Synuclein. JOURNAL OF NEUROSCIENCE RESEARCH, 2001, 65, 432

Klimaschewski L, Nindl W, Pimpl M, Waltinger P, Pfaller K. Biolistic transfection and morphological analysis of cultured sympathetic neurons. JOURNAL OF NEUROSCIENCE METHODS, 2002, 113, 63

Nindl W, Kavakebi P, Claus P, Grothe C, Pfaller K, Klimaschewski L. Expression of FGF-2 isoforms in postmitotic sympathetic neurons: synthesis, nuclear transport and involvement in karyokinesis. NEUROSCIENCE, 2004, 124, 561

Klimaschewski L, Nindl W, Feurle J, Kavakebi P, Kostron H. Basic fibroblast growth factor isoforms promote axonal elongation and branching of adult sensory neurons in vitro. NEUROSCIENCE, 2004, 126, 347

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